Biophysical Electron Paramagnetic Resonance in Structural Biology.

Our lab utilizes site-directed spin labeling and magnetic resonance (EPR and NMR) biophysical approaches to answer questions relevant in cell biology and microbiology. These topics include (a) the association/binding of peptides/proteins with biological membrane surfaces, (b) membrane biophysics (c) membrane protein structure, dynamics, conformational changes, (d) conformational changes in HIV-1 protease (e) "structure" and dynamics of natively unfolded peptides and proteins.