A number of graduate-level biochemistry courses are offered by the Division. To ensure that these courses are accessible
to both biochemistry majors and non-majors, none require undergraduate-level biochemistry as a pre-requisite, although
this experience is helpful. It is strongly recommended that graduate students without a strong biochemistry background
take CHM 5305 (Chemistry of Biological Molecules), which provides a one-semester overview of biochemistry.
CHM 5305 - Chemistry of Biological Molecules. This course
introduces the principles of biochemistry and integrates organic mechanisms. It is strongly recommended for students
interested in joining a group in the Biochemistry Division and also for those whose research in other groups will
involve a strong biochemistry emphasis.
CHM 6301 - Enzyme Mechanisms. An introduction to principles of
enzyme structure, isolation and characterization of enzymes. Transition state theory, types of chemical catalysis and
cofactor chemistry are also discussed.
CHM 6302 - Chemistry and Biology of Nucleic Acids. Principles of nucleic
acid structure and function are discussed in the context of recent research results. There is special emphasis on
sequence-specific protein-DNA binding, DNA and RNA polymerases, mechanisms of phosphate chemistry and the chemical
processes underlying nucleic acid metabolism.
CHM 6303 - Methods in Computational Biochemistry and Structural Biology.
Approaches to protein structure, both modeled and experimental, are discussed in the context of reaction mechanisms.
Both empirical and quantum-mechanical methods are covered. This course provides a good deal of practical experience in
applying computational methods and is recommended for students planning to apply these techniques to their research.
CHM 6304 - Special Topics: Biological Chemistry Mechanisms.
Principles underlying protein structure prediction, molecular evolution, rational protein design and molecular recognition
are discussed. This course offers a significant amount of hands-on computational experience which will allow students
to use these methods in their own research.
CHM 6304 - Special Topics: Chemistry of the Cell. This course is
intended to be a survey of molecular, cellular, and organismal biology from a chemist's perspective. Biochemistry is an
ever-expanding field and a molecular understanding of the basic systems operating within cells and organisms is critical
for success in research.
# CHM 6934 - Advanced Biochemical Topics (Journal
Club). This course provides an opportunity to examine recent research papers critically and builds skills in
effective oral presentations and experimental design.
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